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Induction of 2-hydroxycatecholestrogens O-methylation: A missing puzzle piece in diagnostics and treatment of lung cancer

Lung cancer is one of the most common cancers worldwide, causing nearly one million deaths each year. Herein, we present the effect of 2-methoxyestradiol (2-ME), the endogenous metabolite of 17β-estradiol (E2), on non-small cell lung cancer (NSCLC) cells. We observed that 2-ME reduced the viability...

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Detalles Bibliográficos
Autores principales: Musial, Claudia, Knap, Narcyz, Zaucha, Renata, Bastian, Paulina, Barone, Giampaolo, Lo Bosco, Giosuè, Lo-Celso, Fabrizio, Konieczna, Lucyna, Belka, Mariusz, Bączek, Tomasz, Gammazza, Antonella Marino, Kuban-Jankowska, Alicja, Cappello, Francesco, Nussberger, Stephan, Gorska-Ponikowska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289866/
https://www.ncbi.nlm.nih.gov/pubmed/35841627
http://dx.doi.org/10.1016/j.redox.2022.102395