Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cells

Vasoactive endothelin (ET) is generated by ET converting enzyme (ECE)-induced proteolytic processing of pro-molecule big ET to biologically active peptides. H(2)O(2) has been shown to increase the expression of ECE1 via transactivation of its promoter. The present study demonstrates that H(2)O(2) tr...

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Detalles Bibliográficos
Autores principales: Kumar, Ravi, Soni, Hitesh, Afolabi, Jeremiah M., Kanthakumar, Praghalathan, Mankuzhy, Pratheesh D., Iwhiwhu, Samson A., Adebiyi, Adebowale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289874/
https://www.ncbi.nlm.nih.gov/pubmed/35841629
http://dx.doi.org/10.1016/j.redox.2022.102394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289874/
https://www.ncbi.nlm.nih.gov/pubmed/35841629
http://dx.doi.org/10.1016/j.redox.2022.102394

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