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Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cells
Vasoactive endothelin (ET) is generated by ET converting enzyme (ECE)-induced proteolytic processing of pro-molecule big ET to biologically active peptides. H(2)O(2) has been shown to increase the expression of ECE1 via transactivation of its promoter. The present study demonstrates that H(2)O(2) tr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289874/ https://www.ncbi.nlm.nih.gov/pubmed/35841629 http://dx.doi.org/10.1016/j.redox.2022.102394 |