Rings in Clinical Trials and Drugs: Present and Future

[Image: see text] We present a comprehensive analysis of all ring systems (both heterocyclic and nonheterocyclic) in clinical trial compounds and FDA-approved drugs. We show 67% of small molecules in clinical trials comprise only ring systems found in marketed drugs, which mirrors previously publish...

Descripción completa

Detalles Bibliográficos
Autores principales: Shearer, Jonathan, Castro, Jose L., Lawson, Alastair D. G., MacCoss, Malcolm, Taylor, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289879/
https://www.ncbi.nlm.nih.gov/pubmed/35730680
http://dx.doi.org/10.1021/acs.jmedchem.2c00473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289879/
https://www.ncbi.nlm.nih.gov/pubmed/35730680
http://dx.doi.org/10.1021/acs.jmedchem.2c00473

Ejemplares similares