Cyclic Adenosine Monophosphate (cAMP)‐Dependent Phosphodiesterase Inhibition Promotes Bone Anabolism Through CD8 (+) T Cell Wnt‐10b Production in Mice

Cyclic adenosine monophosphate (cAMP)‐dependent phosphodiesterase (PDE) inhibitors such as pentoxifylline (PTX) suppress cAMP degradation and promote cAMP‐dependent signal transduction. PDE inhibitors increase bone formation and bone mass in preclinical models and are used clinically to treat psoria...

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Detalles Bibliográficos
Autores principales: Roser‐Page, Susanne, Weiss, Daiana, Vikulina, Tatyana, Yu, Mingcan, Pacifici, Roberto, Weitzmann, M. Neale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289889/
https://www.ncbi.nlm.nih.gov/pubmed/35866149
http://dx.doi.org/10.1002/jbm4.10636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289889/
https://www.ncbi.nlm.nih.gov/pubmed/35866149
http://dx.doi.org/10.1002/jbm4.10636

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