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MUC1 expressing tumor growth was retarded after human mucin 1 (MUC1) plasmid DNA immunization

INTRODUCTION: Naked DNA is one of the attractive tools for vaccination studies. We studied naked DNA vaccination against the human tumor antigen, mucin, which is encoded by the MUC1 gene. METHODS: We constructed the pcDNA3.0-MUC1 (pcDNA-MUC1) plasmid expressing an underglycosylated MUC1 protein. BAL...

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Detalles Bibliográficos
Autores principales: Son, Hye-Youn, Jeong, Hwan-Kyu, Apostolopoulos, Vasso, Kim, Chul-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289905/
https://www.ncbi.nlm.nih.gov/pubmed/35839304
http://dx.doi.org/10.1177/03946320221112358