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Interspecies Single‐Cell RNA‐Seq Analysis Reveals the Novel Trajectory of Osteoclast Differentiation and Therapeutic Targets

Bone turnover is finely tuned by cells in the bone milieu, including osteoblasts, osteoclasts, and osteocytes. Osteoclasts are multinucleated giant cells with a bone‐resorbing function that play a critical role in regulating skeletal homeostasis. Osteoclast differentiation is characterized by dramat...

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Detalles Bibliográficos
Autores principales: Omata, Yasunori, Okada, Hiroyuki, Uebe, Steffen, Izawa, Naohiro, Ekici, Arif B., Sarter, Kerstin, Saito, Taku, Schett, Georg, Tanaka, Sakae, Zaiss, Mario M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289986/
https://www.ncbi.nlm.nih.gov/pubmed/35866155
http://dx.doi.org/10.1002/jbm4.10631