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Multicompartmental pharmacokinetic evaluation of long‐acting cabotegravir in healthy adults for HIV preexposure prophylaxis

AIMS: Cabotegravir is an integrase strand transfer inhibitor in clinical development as long‐acting (LA) injectable HIV preexposure prophylaxis. METHODS: This phase I study assessed pharmacokinetics of cabotegravir in plasma and anatomical sites associated with sexual HIV‐1 transmission after repeat...

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Detalles Bibliográficos
Autores principales: Shaik, Jafar Sadik, Weld, Ethel D., Edick, Stacey, Fuchs, Edward, Riddler, Sharon, Marzinke, Mark A., D'Amico, Ronald, Bakshi, Kalpana, Lou, Yu, Hendrix, Craig, Han, Kelong, Ford, Susan L., Margolis, David, Spreen, William, Patel, Parul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290068/
https://www.ncbi.nlm.nih.gov/pubmed/34240467
http://dx.doi.org/10.1111/bcp.14980