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Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC)

Thiazolidinediones are synthetic PPARγ ligands that enhance insulin sensitivity, and that could increase insulin secretion from β‐cells. However, the functional role and mechanism(s) of action in pancreatic β‐cells have not been investigated in detail.

Detalles Bibliográficos
Autores principales: Hwang, Mina, Kim, Hyo‐Sup, Jin, Sang‐Man, Hur, Kyu Yeon, Kim, Jae‐Hyeon, Lee, Moon‐Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290135/
https://www.ncbi.nlm.nih.gov/pubmed/34133753
http://dx.doi.org/10.1002/jcp.30467