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Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC)
Thiazolidinediones are synthetic PPARγ ligands that enhance insulin sensitivity, and that could increase insulin secretion from β‐cells. However, the functional role and mechanism(s) of action in pancreatic β‐cells have not been investigated in detail.
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290135/ https://www.ncbi.nlm.nih.gov/pubmed/34133753 http://dx.doi.org/10.1002/jcp.30467 |
| _version_ | 1784748819178586112 |
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| author | Hwang, Mina Kim, Hyo‐Sup Jin, Sang‐Man Hur, Kyu Yeon Kim, Jae‐Hyeon Lee, Moon‐Kyu |
| author_facet | Hwang, Mina Kim, Hyo‐Sup Jin, Sang‐Man Hur, Kyu Yeon Kim, Jae‐Hyeon Lee, Moon‐Kyu |
| author_sort | Hwang, Mina |
| collection | PubMed |
| description | Thiazolidinediones are synthetic PPARγ ligands that enhance insulin sensitivity, and that could increase insulin secretion from β‐cells. However, the functional role and mechanism(s) of action in pancreatic β‐cells have not been investigated in detail. |
| format | Online Article Text |
| id | pubmed-9290135 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-92901352022-07-20 Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC) Hwang, Mina Kim, Hyo‐Sup Jin, Sang‐Man Hur, Kyu Yeon Kim, Jae‐Hyeon Lee, Moon‐Kyu J Cell Physiol Research Articles Thiazolidinediones are synthetic PPARγ ligands that enhance insulin sensitivity, and that could increase insulin secretion from β‐cells. However, the functional role and mechanism(s) of action in pancreatic β‐cells have not been investigated in detail. John Wiley and Sons Inc. 2021-06-16 2021-12 /pmc/articles/PMC9290135/ /pubmed/34133753 http://dx.doi.org/10.1002/jcp.30467 Text en © 2021 The Authors. Journal of Cellular Physiology published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Research Articles Hwang, Mina Kim, Hyo‐Sup Jin, Sang‐Man Hur, Kyu Yeon Kim, Jae‐Hyeon Lee, Moon‐Kyu Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC) |
| title | Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC) |
| title_full | Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC) |
| title_fullStr | Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC) |
| title_full_unstemmed | Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC) |
| title_short | Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC) |
| title_sort | thiazolidinediones (tzds) enhance insulin secretory response via gpr40 and adenylate cyclase (ac) |
| topic | Research Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290135/ https://www.ncbi.nlm.nih.gov/pubmed/34133753 http://dx.doi.org/10.1002/jcp.30467 |
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