TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma

BACKGROUND: Temozolomide (TMZ) resistance remains the main therapy challenge in patients with glioblastoma multiforme (GBM). TTK Protein Kinase (TTK) contributes to the radioresistance and chemoresistance in many malignancies. However, the role of TTK in the TMZ resistance of GBM cells remains unkno...

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Detalles Bibliográficos
Autores principales: Yu, Jian, Gao, Ge, Wei, Xiangpin, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290216/
https://www.ncbi.nlm.nih.gov/pubmed/35850753
http://dx.doi.org/10.1186/s12885-022-09899-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290216/
https://www.ncbi.nlm.nih.gov/pubmed/35850753
http://dx.doi.org/10.1186/s12885-022-09899-1

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