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TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma
BACKGROUND: Temozolomide (TMZ) resistance remains the main therapy challenge in patients with glioblastoma multiforme (GBM). TTK Protein Kinase (TTK) contributes to the radioresistance and chemoresistance in many malignancies. However, the role of TTK in the TMZ resistance of GBM cells remains unkno...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290216/ https://www.ncbi.nlm.nih.gov/pubmed/35850753 http://dx.doi.org/10.1186/s12885-022-09899-1 |