Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice

The cholinesterase inhibitor donepezil is used to improve Aβ pathology and cognitive function in patients with Alzheimer’s disease (AD). However, the impact of donepezil on tau pathology is unclear. Thus, we examined the effects of donepezil on Aβ and tau pathology in 5xFAD mice (a model of AD) in t...

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Detalles Bibliográficos
Autores principales: Choi, Hee-Jeong, Park, Jin-Hee, Jeong, Yoo Joo, Hwang, Jeong-Woo, Lee, Soojung, Lee, Heeyong, Seol, Eunyoung, Kim, Ik-whi, Cha, Byung-Yoon, Seo, Jinsoo, Moon, Minho, Hoe, Hyang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290238/
https://www.ncbi.nlm.nih.gov/pubmed/35850693
http://dx.doi.org/10.1186/s13041-022-00948-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290238/
https://www.ncbi.nlm.nih.gov/pubmed/35850693
http://dx.doi.org/10.1186/s13041-022-00948-1

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