Cargando…
Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice
The cholinesterase inhibitor donepezil is used to improve Aβ pathology and cognitive function in patients with Alzheimer’s disease (AD). However, the impact of donepezil on tau pathology is unclear. Thus, we examined the effects of donepezil on Aβ and tau pathology in 5xFAD mice (a model of AD) in t...
Autores principales: | Choi, Hee-Jeong, Park, Jin-Hee, Jeong, Yoo Joo, Hwang, Jeong-Woo, Lee, Soojung, Lee, Heeyong, Seol, Eunyoung, Kim, Ik-whi, Cha, Byung-Yoon, Seo, Jinsoo, Moon, Minho, Hoe, Hyang-Sook |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290238/ https://www.ncbi.nlm.nih.gov/pubmed/35850693 http://dx.doi.org/10.1186/s13041-022-00948-1 |
Ejemplares similares
-
The VEGF inhibitor vatalanib regulates AD pathology in 5xFAD mice
por: Jeon, Seong Gak, et al.
Publicado: (2020) -
Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling
por: Kim, Jieun, et al.
Publicado: (2021) -
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD
por: Lee, Hyun-ju, et al.
Publicado: (2023) -
Disruption of the astrocyte–neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer’s disease animal model
por: Choi, Moonseok, et al.
Publicado: (2021) -
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy
por: Kim, Jieun, et al.
Publicado: (2023)