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Andrographolide protects bone marrow mesenchymal stem cells against glucose and serum deprivation under hypoxia via the NRF2 signaling pathway

BACKGROUND: Bone marrow mesenchymal stem cell (BMSCs) therapy is an important cell transplantation strategy in the regenerative medicine field. However, a severely ischemic microenvironment, such as nutrient depletion and hypoxia, causes a lower survival rate of transplanted BMSCs, limiting the appl...

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Detalles Bibliográficos
Autores principales: Sun, Yanting, Xu, Hao, Tan, Bin, Yi, Qin, Liu, Huiwen, Chen, Tangtian, Xiang, Han, Wang, Rui, Xie, Qiumin, Tian, Jie, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290240/
https://www.ncbi.nlm.nih.gov/pubmed/35850702
http://dx.doi.org/10.1186/s13287-022-03016-6