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DNA methylation subtypes guiding prognostic assessment and linking to responses the DNA methyltransferase inhibitor SGI-110 in urothelial carcinoma

BACKGROUND: At present, the extent and clinical relevance of epigenetic differences between upper tract urothelial carcinoma (UTUC) and urothelial carcinoma of the bladder (UCB) remain largely unknown. Here, we conducted a study to describe the global DNA methylation landscape of UTUC and UCB and to...

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Detalles Bibliográficos
Autores principales: Li, Juan, Liang, Yuan, Fan, Jian, Xu, Chunru, Guan, Bao, Zhang, Jianye, Guo, Bin, Shi, Yue, Wang, Ping, Tan, Yezhen, Zhang, Qi, Yuan, Changwei, Wu, Yucai, Zhou, Liqun, Ci, Weimin, Li, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290251/
https://www.ncbi.nlm.nih.gov/pubmed/35843958
http://dx.doi.org/10.1186/s12916-022-02426-w