Cargando…

High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression

Cell senescence is a basic aging mechanism. Previous studies have found that the cellular senescence in adipose tissue and other tissues, such as the pancreas, muscle and liver, is associated with the pathogenesis and progression of type 2 diabetes; however, strong evidence of whether diabetes direc...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Wen-Jiao, He, Cheng-Feng, Zhou, Ren-Yuan, Xu, Xiao-Die, Xiang, Lv-Xuan, Wang, Jian-Tao, Wang, Xin-Ru, Zhou, Hou-Guang, Guo, Jing-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290252/
https://www.ncbi.nlm.nih.gov/pubmed/35850767
http://dx.doi.org/10.1186/s13041-022-00947-2