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RA signaling pathway combined with Wnt signaling pathway regulates human-induced pluripotent stem cells (hiPSCs) differentiation to sinus node-like cells

BACKGROUND: The source of SAN is debated among researchers. Many studies have shown that RA and Wnt signaling are involved in heart development. In this study, we investigated the role of retinoic acid (RA) and Wnt signaling in the induction of sinus node-like cells. METHODS: The experimental sample...

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Detalles Bibliográficos
Autores principales: Yin, Lin, Wang, Feng-yuan, Zhang, Wei, Wang, Xi, Tang, Yan-hong, Wang, Teng, Chen, Yu-ting, Huang, Cong-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290266/
https://www.ncbi.nlm.nih.gov/pubmed/35851424
http://dx.doi.org/10.1186/s13287-022-03006-8