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RA signaling pathway combined with Wnt signaling pathway regulates human-induced pluripotent stem cells (hiPSCs) differentiation to sinus node-like cells
BACKGROUND: The source of SAN is debated among researchers. Many studies have shown that RA and Wnt signaling are involved in heart development. In this study, we investigated the role of retinoic acid (RA) and Wnt signaling in the induction of sinus node-like cells. METHODS: The experimental sample...
Autores principales: | Yin, Lin, Wang, Feng-yuan, Zhang, Wei, Wang, Xi, Tang, Yan-hong, Wang, Teng, Chen, Yu-ting, Huang, Cong-xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290266/ https://www.ncbi.nlm.nih.gov/pubmed/35851424 http://dx.doi.org/10.1186/s13287-022-03006-8 |
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