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The HeMoVal study protocol: a prospective international multicenter cohort study to validate cerebrospinal fluid hemoglobin as a monitoring biomarker for aneurysmal subarachnoid hemorrhage related secondary brain injury

INTRODUCTION: Preclinical studies provided a strong rationale for a pathophysiological link between cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) and secondary brain injury after subarachnoid hemorrhage (SAH-SBI). In a single-center prospective observational clinical study, external ventr...

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Detalles Bibliográficos
Autores principales: Akeret, Kevin, Buzzi, Raphael M., Saxenhofer, Moritz, Bieri, Kathrin, Chiavi, Deborah, Thomson, Bart R., Grüttner-Durmaz, Manuela, Schwendinger, Nina, Humar, Rok, Regli, Luca, van Doormaal, Tristan P. C., Held, Ulrike, Keller, Emanuela, Hugelshofer, Michael, Schaer, Dominik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290286/
https://www.ncbi.nlm.nih.gov/pubmed/35850705
http://dx.doi.org/10.1186/s12883-022-02789-w