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The HeMoVal study protocol: a prospective international multicenter cohort study to validate cerebrospinal fluid hemoglobin as a monitoring biomarker for aneurysmal subarachnoid hemorrhage related secondary brain injury
INTRODUCTION: Preclinical studies provided a strong rationale for a pathophysiological link between cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) and secondary brain injury after subarachnoid hemorrhage (SAH-SBI). In a single-center prospective observational clinical study, external ventr...
Autores principales: | Akeret, Kevin, Buzzi, Raphael M., Saxenhofer, Moritz, Bieri, Kathrin, Chiavi, Deborah, Thomson, Bart R., Grüttner-Durmaz, Manuela, Schwendinger, Nina, Humar, Rok, Regli, Luca, van Doormaal, Tristan P. C., Held, Ulrike, Keller, Emanuela, Hugelshofer, Michael, Schaer, Dominik J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290286/ https://www.ncbi.nlm.nih.gov/pubmed/35850705 http://dx.doi.org/10.1186/s12883-022-02789-w |
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