SARS-CoV-2 spike protein inhibits megalin-mediated albumin endocytosis in proximal tubule epithelial cells

Patients with COVID-19 have high prevalence of albuminuria which is used as a marker of progression of renal disease and is associated with severe COVID-19. We hypothesized that SARS-CoV-2 spike protein (S protein) could modulate albumin handling in proximal tubule epithelial cells (PTECs) and, cons...

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Detalles Bibliográficos
Autores principales: Silva-Aguiar, Rodrigo P., Teixeira, Douglas E., Peruchetti, Diogo B., Florentino, Lucas S., Peres, Rodrigo A.S., Gomes, Carlos P., Marzolo, Maria-Paz, Rocco, Patricia M.R., Pinheiro, Ana Acacia S., Caruso-Neves, Celso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290338/
https://www.ncbi.nlm.nih.gov/pubmed/35863591
http://dx.doi.org/10.1016/j.bbadis.2022.166496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290338/
https://www.ncbi.nlm.nih.gov/pubmed/35863591
http://dx.doi.org/10.1016/j.bbadis.2022.166496

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