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High DNMT1 Is Associated With Worse Local Control in Early‐Stage Laryngeal Squamous Cell Carcinoma

OBJECTIVES/HYPOTHESIS: Early‐stage laryngeal squamous cell carcinoma (LSCC) has yielded local control rates of 75% after radiotherapy. DNA methylation, in which DNA methyltransferases play an important role, has influence on tumorigenesis. In this study, we investigated the association between the e...

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Detalles Bibliográficos
Autores principales: Bruine de Bruin, Leonie, Clausen, Martijn J. A. M., Slagter‐Menkema, Lorian, de Bock, Gertruida H, Langendijk, Johannes A., van der Vegt, Bert, van der Laan, Bernard F. A. M., Schuuring, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290472/
https://www.ncbi.nlm.nih.gov/pubmed/34427325
http://dx.doi.org/10.1002/lary.29833