The importance of ethnicity: Are breast cancer polygenic risk scores ready for women who are not of White European origin?

Polygenic risk scores (PRS) for disease risk stratification show great promise for application in general populations, but most are based on data from individuals of White European origin. We assessed two well validated PRS (SNP18, SNP143) in the Predicting‐Risk‐of‐Cancer‐At‐Screening (PROCAS) study...

Descripción completa

Detalles Bibliográficos
Autores principales: Evans, D. Gareth, van Veen, Elke M., Byers, Helen, Roberts, Eleanor, Howell, Anthony, Howell, Sacha J., Harkness, Elaine F., Brentnall, Adam, Cuzick, Jack, Newman, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Cancer Genetics and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290473/
https://www.ncbi.nlm.nih.gov/pubmed/34460111
http://dx.doi.org/10.1002/ijc.33782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290473/
https://www.ncbi.nlm.nih.gov/pubmed/34460111
http://dx.doi.org/10.1002/ijc.33782

Ejemplares similares