Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity

BACKGROUND AND PURPOSE: Individualized assessment of cytochrome P450 2D6 (CYP2D6) activity is usually performed through phenotyping following administration of a probe drug to measure the enzyme's activity. To avoid any iatrogenic harm (allergic drug reaction, dosing error) related to the probe...

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Detalles Bibliográficos
Autores principales: Magliocco, Gaëlle, Desmeules, Jules, Matthey, Alain, Quirós‐Guerrero, Luis M., Bararpour, Nasim, Joye, Timothée, Marcourt, Laurence, Queiroz, Emerson F., Wolfender, Jean‐Luc, Gloor, Yvonne, Thomas, Aurélien, Daali, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290485/
https://www.ncbi.nlm.nih.gov/pubmed/34363609
http://dx.doi.org/10.1111/bph.15651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290485/
https://www.ncbi.nlm.nih.gov/pubmed/34363609
http://dx.doi.org/10.1111/bph.15651

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