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B4GALNT2 Controls Sd(a) and SLe(x) Antigen Biosynthesis in Healthy and Cancer Human Colon

The Sd(a) carbohydrate antigen and the corresponding biosynthetic enzyme B4GALNT2 are primarily expressed in human normal colonic mucosa and are down‐regulated to variable degrees in colon cancer. On the other hand, the tumor associated antigen SLe(x) is not detected in the healthy colon and is upre...

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Detalles Bibliográficos
Autores principales: Groux‐Degroote, Sophie, Vicogne, Dorothée, Cogez, Virginie, Schulz, Céline, Harduin‐Lepers, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290495/
https://www.ncbi.nlm.nih.gov/pubmed/34397142
http://dx.doi.org/10.1002/cbic.202100363