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Abnormal whisker-dependent behaviors and altered cortico-hippocampal connectivity in Shank3b(−/−) mice
Abnormal tactile response is an integral feature of Autism Spectrum Disorders (ASDs), and hypo-responsiveness to tactile stimuli is often associated with the severity of ASDs core symptoms. Patients with Phelan-McDermid syndrome (PMS), caused by mutations in the SHANK3 gene, show ASD-like symptoms a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290535/ https://www.ncbi.nlm.nih.gov/pubmed/34791077 http://dx.doi.org/10.1093/cercor/bhab399 |