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Abnormal whisker-dependent behaviors and altered cortico-hippocampal connectivity in Shank3b(−/−) mice

Abnormal tactile response is an integral feature of Autism Spectrum Disorders (ASDs), and hypo-responsiveness to tactile stimuli is often associated with the severity of ASDs core symptoms. Patients with Phelan-McDermid syndrome (PMS), caused by mutations in the SHANK3 gene, show ASD-like symptoms a...

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Detalles Bibliográficos
Autores principales: Balasco, Luigi, Pagani, Marco, Pangrazzi, Luca, Chelini, Gabriele, Ciancone Chama, Alessandra Georgette, Shlosman, Evgenia, Mattioni, Lorenzo, Galbusera, Alberto, Iurilli, Giuliano, Provenzano, Giovanni, Gozzi, Alessandro, Bozzi, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290535/
https://www.ncbi.nlm.nih.gov/pubmed/34791077
http://dx.doi.org/10.1093/cercor/bhab399