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Abnormal whisker-dependent behaviors and altered cortico-hippocampal connectivity in Shank3b(−/−) mice
Abnormal tactile response is an integral feature of Autism Spectrum Disorders (ASDs), and hypo-responsiveness to tactile stimuli is often associated with the severity of ASDs core symptoms. Patients with Phelan-McDermid syndrome (PMS), caused by mutations in the SHANK3 gene, show ASD-like symptoms a...
Autores principales: | Balasco, Luigi, Pagani, Marco, Pangrazzi, Luca, Chelini, Gabriele, Ciancone Chama, Alessandra Georgette, Shlosman, Evgenia, Mattioni, Lorenzo, Galbusera, Alberto, Iurilli, Giuliano, Provenzano, Giovanni, Gozzi, Alessandro, Bozzi, Yuri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290535/ https://www.ncbi.nlm.nih.gov/pubmed/34791077 http://dx.doi.org/10.1093/cercor/bhab399 |
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