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De novo Mutations in Domestic Cat are Consistent with an Effect of Reproductive Longevity on Both the Rate and Spectrum of Mutations

The mutation rate is a fundamental evolutionary parameter with direct and appreciable effects on the health and function of individuals. Here, we examine this important parameter in the domestic cat, a beloved companion animal as well as a valuable biomedical model. We estimate a mutation rate of 0....

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Detalles Bibliográficos
Autores principales: Wang, Richard J, Raveendran, Muthuswamy, Harris, R Alan, Murphy, William J, Lyons, Leslie A, Rogers, Jeffrey, Hahn, Matthew W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290555/
https://www.ncbi.nlm.nih.gov/pubmed/35771663
http://dx.doi.org/10.1093/molbev/msac147