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Mutual Prodrugs of 5‐Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs

The development of potent antitumor agents with a low toxicological profile against healthy cells is still one of the greatest challenges facing medicinal chemistry. In this context, the “mutual prodrug” approach has emerged as a potential tool to overcome undesirable physicochemical features and mi...

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Detalles Bibliográficos
Autores principales: Ciaffaglione, Valeria, Modica, Maria N., Pittalà, Valeria, Romeo, Giuseppe, Salerno, Loredana, Intagliata, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290623/
https://www.ncbi.nlm.nih.gov/pubmed/34415107
http://dx.doi.org/10.1002/cmdc.202100473