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Mutual Prodrugs of 5‐Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs
The development of potent antitumor agents with a low toxicological profile against healthy cells is still one of the greatest challenges facing medicinal chemistry. In this context, the “mutual prodrug” approach has emerged as a potential tool to overcome undesirable physicochemical features and mi...
Autores principales: | Ciaffaglione, Valeria, Modica, Maria N., Pittalà, Valeria, Romeo, Giuseppe, Salerno, Loredana, Intagliata, Sebastiano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290623/ https://www.ncbi.nlm.nih.gov/pubmed/34415107 http://dx.doi.org/10.1002/cmdc.202100473 |
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