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Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis

Acumulation of oxidized membrane lipids ultimately results in ferroptotic cell death, which can be prevented by the selenoenzyme glutathione peroxidase 4 (Gpx4). In vivo conditions promoting ferroptosis and susceptible cell types are still poorly defined. In this study, we analyzed the conditional d...

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Detalles Bibliográficos
Autores principales: Piattini, Federica, Matsushita, Mai, Muri, Jonathan, Bretscher, Peter, Feng, Xiaogang, Freigang, Stefan, Dalli, Jesmond, Schneider, Christoph, Kopf, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290640/
https://www.ncbi.nlm.nih.gov/pubmed/34272880
http://dx.doi.org/10.1002/eji.202049114