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Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI
The in vivo comet assay can evaluate the genotoxic potential of a chemical in theoretically any tissue that can be processed to a single cell suspension. This flexibility enables evaluation of point‐of‐contact tissues using a relevant route of test material administration; however, assessing cytotox...
Autores principales: | Ji, Zhiying, Koehler, Matthew W., Scott, Andrew B., LeBaron, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290646/ https://www.ncbi.nlm.nih.gov/pubmed/34369617 http://dx.doi.org/10.1002/em.22457 |
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