Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers

AIMS: Whereas intravenous administration of Toll‐like receptor 4 ligand lipopolysaccharide (LPS) to human volunteers is frequently used in clinical pharmacology studies, systemic use of LPS has practical limitations. We aimed to characterize the intradermal LPS response in healthy volunteers, and as...

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Detalles Bibliográficos
Autores principales: Buters, Thomas P., Hameeteman, Pieter W., Jansen, Iris M. E., van Hindevoort, Floris C., ten Voorde, Wouter, Florencia, Edwin, Osse, Michelle, de Kam, Marieke L., Grievink, Hendrika W., Schoonakker, Mascha, Patel, Amit A., Yona, Simon, Gilroy, Derek W., Lubberts, Erik, Damman, Jeffrey, Feiss, Gary, Rissmann, Robert, Jansen, Manon A. A., Burggraaf, Jacobus, Moerland, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290695/
https://www.ncbi.nlm.nih.gov/pubmed/34293819
http://dx.doi.org/10.1111/bcp.14999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290695/
https://www.ncbi.nlm.nih.gov/pubmed/34293819
http://dx.doi.org/10.1111/bcp.14999

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