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Multiparametric magnetic resonance imaging to characterize cabotegravir long‐acting formulation depot kinetics in healthy adult volunteers

AIM: Cabotegravir long‐acting (LA) intramuscular (IM) injection is being investigated for HIV preexposure prophylaxis due to its potent antiretroviral activity and infrequent dosing requirement. A subset of healthy adult volunteers participating in a Phase I study assessing cabotegravir tissue pharm...

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Detalles Bibliográficos
Autores principales: Jucker, Beat M., Fuchs, Edward J., Lee, Sarah, Damian, Valeriu, Galette, Paul, Janiczek, Robert, Macura, Katarzyna J., Jacobs, Michael A., Weld, Ethel D., Solaiyappan, Meiyappan, D'Amico, Ronald, Shaik, Jafar Sadik, Bakshi, Kalpana, Han, Kelong, Ford, Susan, Margolis, David, Spreen, William, Gupta, Manish K., Hendrix, Craig W., Patel, Parul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290983/
https://www.ncbi.nlm.nih.gov/pubmed/34240449
http://dx.doi.org/10.1111/bcp.14977