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Whole genome sequencing identifies rare germline variants enriched in cancer related genes in first degree relatives of familial pancreatic cancer patients

First‐degree relatives (FDRs) of familial pancreatic cancer (FPC) patients have increased risk of developing pancreatic ductal adenocarcinoma (PDAC). Investigating and understanding the genetic basis for PDAC susceptibility in FPC predisposed families may contribute toward future risk‐assessment and...

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Detalles Bibliográficos
Autores principales: Tan, Ming, Brusgaard, Klaus, Gerdes, Anne‐Marie, Mortensen, Michael Bau, Detlefsen, Sönke, Schaffalitzky de Muckadell, Ove B., Joergensen, Maiken Thyregod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291090/
https://www.ncbi.nlm.nih.gov/pubmed/34313325
http://dx.doi.org/10.1111/cge.14038