IRE1 signaling regulates chondrocyte apoptosis and death fate in the osteoarthritis

IRE1 is an important central regulator of unfolded protein response (UPR) in the endoplasmic reticulum (ER) because of its ability to regulate cell fate as a function of stress sensing. When misfolded proteins accumulated in chondrocytes ER, IRE1 disintegrates with BIP/GRP78 and undergoes dimer/olig...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Rongxiang, Hui, Zhang, Wei, Sun, Li, Duan, Li, Wencui, Daping, Wang, Alahdal, Murad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291116/
https://www.ncbi.nlm.nih.gov/pubmed/34297411
http://dx.doi.org/10.1002/jcp.30537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291116/
https://www.ncbi.nlm.nih.gov/pubmed/34297411
http://dx.doi.org/10.1002/jcp.30537

Ejemplares similares