Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus

BACKGROUND: Interleukin (IL)‐31 is a cytokine involved in allergic inflammation which induces pruritus across species including dogs. Using recombinant canine IL‐31 we have developed a model of pruritus in the dog to evaluate onset of action and duration of effect of therapeutic drugs. OBJECTIVE: To...

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Detalles Bibliográficos
Autores principales: Fleck, Timothy J., Norris, Lori R., Mahabir, Sean, Walters, Rodney R., Martinon, Olivier, Dunham, Steven A., Gonzales, Andrea J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Supporting Original Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291138/
https://www.ncbi.nlm.nih.gov/pubmed/33830571
http://dx.doi.org/10.1111/vde.12943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291138/
https://www.ncbi.nlm.nih.gov/pubmed/33830571
http://dx.doi.org/10.1111/vde.12943

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