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Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation

Rearrangement of the actin cytoskeleton is critical for cytotoxic and immunoregulatory functions as well as migration of natural killer (NK) cells. However, dynamic reorganization of actin is a complex process, which remains largely unknown. Here, we investigated the role of the protein Cereblon (CR...

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Detalles Bibliográficos
Autores principales: Fionda, Cinzia, Stabile, Helena, Molfetta, Rosa, Kosta, Andrea, Peruzzi, Giovanna, Ruggeri, Silvia, Zingoni, Alessandra, Capuano, Cristina, Soriani, Alessandra, Paolini, Rossella, Gismondi, Angela, Cippitelli, Marco, Santoni, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291148/
https://www.ncbi.nlm.nih.gov/pubmed/34392531
http://dx.doi.org/10.1002/eji.202149269