Mechanical Counterbalance of Kinesin and Dynein Motors in a Microtubular Network Regulates Cell Mechanics, 3D Architecture, and Mechanosensing

[Image: see text] Microtubules (MTs) and MT motor proteins form active 3D networks made of unstretchable cables with rod-like bending mechanics that provide cells with a dynamically changing structural scaffold. In this study, we report an antagonistic mechanical balance within the dynein–kinesin mi...

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Detalles Bibliográficos
Autores principales: Zhovmer, Alexander S., Manning, Alexis, Smith, Chynna, Hayes, James B., Burnette, Dylan T., Wang, Jian, Cartagena-Rivera, Alexander X., Dokholyan, Nikolay V., Singh, Rakesh K., Tabdanov, Erdem D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291236/
https://www.ncbi.nlm.nih.gov/pubmed/34677937
http://dx.doi.org/10.1021/acsnano.1c04435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291236/
https://www.ncbi.nlm.nih.gov/pubmed/34677937
http://dx.doi.org/10.1021/acsnano.1c04435

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