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Mechanical Counterbalance of Kinesin and Dynein Motors in a Microtubular Network Regulates Cell Mechanics, 3D Architecture, and Mechanosensing
[Image: see text] Microtubules (MTs) and MT motor proteins form active 3D networks made of unstretchable cables with rod-like bending mechanics that provide cells with a dynamically changing structural scaffold. In this study, we report an antagonistic mechanical balance within the dynein–kinesin mi...
Autores principales: | Zhovmer, Alexander S., Manning, Alexis, Smith, Chynna, Hayes, James B., Burnette, Dylan T., Wang, Jian, Cartagena-Rivera, Alexander X., Dokholyan, Nikolay V., Singh, Rakesh K., Tabdanov, Erdem D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291236/ https://www.ncbi.nlm.nih.gov/pubmed/34677937 http://dx.doi.org/10.1021/acsnano.1c04435 |
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