SOD1 mediates lysosome-to-mitochondria communication and its dysregulation by amyloid-β oligomers

Altered mitochondrial DNA (mtDNA) occurs in neurodegenerative disorders like Alzheimer’s disease (AD); how mtDNA synthesis is linked to neurodegeneration is poorly understood. We previously discovered Nutrient-induced Mitochondrial Activity (NiMA), an inter-organelle signaling pathway where nutrient...

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Detalles Bibliográficos
Autores principales: Norambuena, Andrés, Sun, Xuehan, Wallrabe, Horst, Cao, Ruofan, Sun, Naidi, Pardo, Evelyn, Shivange, Nutan, Wang, Dora Bigler, Post, Lisa A., Ferris, Heather A., Hu, Song, Periasamy, Ammasi, Bloom, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291271/
https://www.ncbi.nlm.nih.gov/pubmed/35452786
http://dx.doi.org/10.1016/j.nbd.2022.105737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291271/
https://www.ncbi.nlm.nih.gov/pubmed/35452786
http://dx.doi.org/10.1016/j.nbd.2022.105737

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