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Clinical characteristics of human platelet antigen (HPA)‐1a and HPA‐5b alloimmunised pregnancies and the association between platelet HPA‐5b antibodies and symptomatic fetal neonatal alloimmune thrombocytopenia

Fetal neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloantibodies directed against the human platelet antigens (mostly HPA‐1a or HPA‐5b) of the (unborn) child and can lead to severe bleeding. Anti‐HPA‐1a‐mediated FNAIT shows a severe clinical outcome more often than anti‐HPA‐5b...

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Detalles Bibliográficos
Autores principales: de Vos, Thijs W., Porcelijn, Leendert, Hofstede‐van Egmond, Suzanne, Pajkrt, Eva, Oepkes, Dick, Lopriore, Enrico, van der Schoot, C. Ellen, Winkelhorst, Dian, de Haas, Masja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291578/
https://www.ncbi.nlm.nih.gov/pubmed/34402048
http://dx.doi.org/10.1111/bjh.17731