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Clinical characteristics of human platelet antigen (HPA)‐1a and HPA‐5b alloimmunised pregnancies and the association between platelet HPA‐5b antibodies and symptomatic fetal neonatal alloimmune thrombocytopenia
Fetal neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloantibodies directed against the human platelet antigens (mostly HPA‐1a or HPA‐5b) of the (unborn) child and can lead to severe bleeding. Anti‐HPA‐1a‐mediated FNAIT shows a severe clinical outcome more often than anti‐HPA‐5b...
Autores principales: | de Vos, Thijs W., Porcelijn, Leendert, Hofstede‐van Egmond, Suzanne, Pajkrt, Eva, Oepkes, Dick, Lopriore, Enrico, van der Schoot, C. Ellen, Winkelhorst, Dian, de Haas, Masja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291578/ https://www.ncbi.nlm.nih.gov/pubmed/34402048 http://dx.doi.org/10.1111/bjh.17731 |
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