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A novel yeast‐based screening system for potential compounds that can alleviate human α‐synuclein toxicity

AIMS: This study aimed to establish a yeast‐based screening system for potential compounds that can alleviate the toxicity of α‐synuclein (α‐syn), a neuropathological hallmark of Parkinson’s disease, either inhibition of α‐syn aggregation or promotion of ubiquitin‐mediated degradation of α‐syn. METH...

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Detalles Bibliográficos
Autores principales: Sangkaew, Anyaporn, Kojornna, Thanaporn, Tanahashi, Ryoya, Takagi, Hiroshi, Yompakdee, Chulee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291589/
https://www.ncbi.nlm.nih.gov/pubmed/34448525
http://dx.doi.org/10.1111/jam.15256