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A benchmark for dose-finding studies with unknown ordering

An important tool to evaluate the performance of a dose-finding design is the nonparametric optimal benchmark that provides an upper bound on the performance of a design under a given scenario. A fundamental assumption of the benchmark is that the investigator can arrange doses in a monotonically in...

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Detalles Bibliográficos
Autores principales: Mozgunov, Pavel, Paoletti, Xavier, Jaki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291639/
https://www.ncbi.nlm.nih.gov/pubmed/33409536
http://dx.doi.org/10.1093/biostatistics/kxaa054