High-throughput profiling of antibody self-association in multiple formulation conditions by PEG stabilized self-interaction nanoparticle spectroscopy

Affinity-capture self-interaction nanoparticle spectroscopy (AC-SINS) is an assay developed to monitor the propensity of antibody self-association, hence assessing its colloidal stability. It has been widely used by pharmaceutical companies to screen antibodies at the early discovery stages, aiming...

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Detalles Bibliográficos
Autores principales: Phan, Samantha, Walmer, Auralee, Shaw, Eudean W., Chai, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291693/
https://www.ncbi.nlm.nih.gov/pubmed/35830420
http://dx.doi.org/10.1080/19420862.2022.2094750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291693/
https://www.ncbi.nlm.nih.gov/pubmed/35830420
http://dx.doi.org/10.1080/19420862.2022.2094750

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