Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-tumor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response

Immune checkpoint inhibitors (ICIs) have revolutionized the oncology field. However, a significant number of patients do not respond, at least partly due to the lack of preexisting anti-tumor T-cell immunity. Therefore, it is emergent to add an immune-priming step to improve efficacy. Here, we repor...

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Detalles Bibliográficos
Autores principales: Jin, Chuan, Ali, Arwa, Iskantar, Alexandros, Fotaki, Grammatiki, Wang, Hai, Essand, Magnus, Karlsson-Parra, Alex, Yu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291714/
https://www.ncbi.nlm.nih.gov/pubmed/35859733
http://dx.doi.org/10.1080/2162402X.2022.2099642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291714/
https://www.ncbi.nlm.nih.gov/pubmed/35859733
http://dx.doi.org/10.1080/2162402X.2022.2099642

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