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Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-tumor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent response
Immune checkpoint inhibitors (ICIs) have revolutionized the oncology field. However, a significant number of patients do not respond, at least partly due to the lack of preexisting anti-tumor T-cell immunity. Therefore, it is emergent to add an immune-priming step to improve efficacy. Here, we repor...
Autores principales: | Jin, Chuan, Ali, Arwa, Iskantar, Alexandros, Fotaki, Grammatiki, Wang, Hai, Essand, Magnus, Karlsson-Parra, Alex, Yu, Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291714/ https://www.ncbi.nlm.nih.gov/pubmed/35859733 http://dx.doi.org/10.1080/2162402X.2022.2099642 |
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