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The Effect of Food on the Pharmacokinetics of the Potassium‐Competitive Acid Blocker Vonoprazan

Herein, we report a food‐effect study of vonoprazan, an oral potassium‐competitive acid blocker. In a phase 1, randomized, open‐label, crossover study, healthy subjects received a single 20‐mg dose of vonoprazan either following an overnight fast or 30 minutes after a high‐fat breakfast. Plasma vono...

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Detalles Bibliográficos
Autores principales: Mulford, Darcy J., Leifke, Eckhard, Hibberd, Mark, Howden, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291755/
https://www.ncbi.nlm.nih.gov/pubmed/34431240
http://dx.doi.org/10.1002/cpdd.1009